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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH18A1
All Species:
27.88
Human Site:
S143
Identified Species:
43.81
UniProt:
P54886
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54886
NP_001017423.1
795
87302
S143
S
V
R
Q
A
L
H
S
G
Q
N
Q
L
K
E
Chimpanzee
Pan troglodytes
XP_001155890
796
87730
S143
S
V
R
Q
A
L
H
S
G
Q
N
Q
L
K
E
Rhesus Macaque
Macaca mulatta
XP_001099359
795
87154
S143
S
V
R
Q
A
L
H
S
G
Q
N
Q
L
K
E
Dog
Lupus familis
XP_534976
795
87233
S143
S
V
R
Q
A
L
H
S
G
Q
N
Q
L
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z110
795
87278
S143
S
V
R
Q
A
L
H
S
G
Q
N
H
L
K
E
Rat
Rattus norvegicus
NP_001101994
795
87311
S143
S
V
R
Q
A
L
H
S
G
Q
N
H
L
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508419
607
66410
T20
K
R
R
N
L
N
G
T
L
H
E
L
L
R
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086040
815
89190
S144
S
V
R
Q
A
L
H
S
G
Q
N
Q
L
K
D
Zebra Danio
Brachydanio rerio
NP_001077015
782
85358
R139
S
L
P
V
L
E
A
R
A
C
A
A
A
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649375
776
84074
A138
D
S
K
E
F
D
G
A
T
L
E
P
R
A
A
Honey Bee
Apis mellifera
XP_396399
732
79216
E138
K
P
D
F
Y
N
E
E
T
R
N
N
L
F
S
Nematode Worm
Caenorhab. elegans
P54889
800
86509
G152
S
M
R
Q
T
L
R
G
P
S
G
M
T
A
D
Sea Urchin
Strong. purpuratus
XP_781524
752
81324
V138
Y
G
L
T
T
A
Q
V
L
V
T
K
P
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P54888
726
78853
E139
D
F
R
K
Q
L
S
E
T
V
K
A
M
L
R
Baker's Yeast
Sacchar. cerevisiae
P54885
456
49722
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.9
97.4
97.1
N.A.
95.3
95.2
N.A.
71.6
N.A.
84.4
82.1
N.A.
55.9
54.7
52.5
56.4
Protein Similarity:
100
94.9
98.2
98.6
N.A.
97.7
97.4
N.A.
74.9
N.A.
90.8
91.5
N.A.
70.8
69.5
69.5
73.3
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
93.3
6.6
N.A.
0
13.3
26.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
N.A.
100
20
N.A.
20
20
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.6
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.1
38.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
47
7
7
7
7
0
7
14
7
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
14
0
7
0
0
7
0
0
0
0
0
0
0
7
14
% D
% Glu:
0
0
0
7
0
7
7
14
0
0
14
0
0
0
40
% E
% Phe:
0
7
0
7
7
0
0
0
0
0
0
0
0
7
7
% F
% Gly:
0
7
0
0
0
0
14
7
47
0
7
0
0
7
0
% G
% His:
0
0
0
0
0
0
47
0
0
7
0
14
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
14
0
7
7
0
0
0
0
0
0
7
7
0
47
0
% K
% Leu:
0
7
7
0
14
60
0
0
14
7
0
7
60
7
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
7
7
0
7
% M
% Asn:
0
0
0
7
0
14
0
0
0
0
54
7
0
0
0
% N
% Pro:
0
7
7
0
0
0
0
0
7
0
0
7
7
0
0
% P
% Gln:
0
0
0
54
7
0
7
0
0
47
0
34
0
0
7
% Q
% Arg:
0
7
67
0
0
0
7
7
0
7
0
0
7
7
7
% R
% Ser:
60
7
0
0
0
0
7
47
0
7
0
0
0
0
7
% S
% Thr:
0
0
0
7
14
0
0
7
20
0
7
0
7
0
0
% T
% Val:
0
47
0
7
0
0
0
7
0
14
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _